Aspirin as a neoadjuvant agent during preoperative chemoradiation for rectal cancer
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چکیده
منابع مشابه
New drug in neoadjuvant chemoradiation for rectal cancer
Background: In recent years, neoadjuvant chemoradiation and subsequent surgical resection with total mesorectal excision has been shown to increase local control with decreased toxicity. Neoadjuvant chemoradiotherapy is the standard treatment for locally advanced rectal cancer. In this study we evaluated the efficacy a cox-2 inhibitor on pathologic response, sphincter preservation and acute tox...
متن کاملnew drug in neoadjuvant chemoradiation for rectal cancer
background: in recent years, neoadjuvant chemoradiation and subsequent surgical resection with total mesorectal excision has been shown to increase local control with decreased toxicity. neoadjuvant chemoradiotherapy is the standard treatment for locally advanced rectal cancer. in this study we evaluated the efficacy a cox-2 inhibitor on pathologic response, sphincter preservation and acute tox...
متن کاملPreoperative Chemoradiation Therapy for Rectal Cancer.
The surgeon and the radiation therapist share the primary responsibility for the maintenance of local control in the management of carcinoma of the rectum. Usually, radiation therapy is used to control microscopic disease, while surgery is employed to control macroscopic disease. For ionizing radiation to be effective, targeted tissues must be well oxygenated. Likewise, the risk of local recurr...
متن کاملComparison between intensified neoadjuvant treatment and standard preoperative chemoradiation for rectal cancer.
OBJECTIVES The aim of the current study was to compare a neoadjuvant regimen containing oxaliplatin with standard preoperative treatment for rectal cancer. METHODS From December 2006 to December 2007, 20 patients with rectal cancer were treated at our Institution with the weekly addition of oxaliplatin (50 mg/m(2)) to radiotherapy (50.4-54.0 Gy in 28-30 daily fractions) and continuous infusio...
متن کاملComparison of 5FU-base Chemoradiation with and without Eloxatin on Pathologic Complete Response in Neoadjuvant Chemoradiation of Rectal cancer
Background and Objectives: To compare pathologic complete response (pCR) in patients with advanced rectal cancer receiving neoadjuvant chemoradiotherapy (NACT) by 5-FU or Xeloda (capecitabine) with and without Eloxatin (oxaloplatin injection). Materials and Methods: Seventy-five consecutive patients with the diagnosis of advanced rectal adenocarcinoma were included. Two basic chemotherapy r...
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ژورنال
عنوان ژورنال: British Journal of Cancer
سال: 2015
ISSN: 0007-0920,1532-1827
DOI: 10.1038/bjc.2015.336